H.264, MPEG-4′s advanced codec featured in the iPod, the Sony PSP, and both Blu-Ray and HD-DVD, as well as future broadcast video standards, has a lot of skeptics. Many say H.264 doesn’t have a lot to offer people when videos are compressed at the higher bitrates required for HD content (self-contradictory, as H.264 is accepted as the standard MPEG-4 codec for High Definition).
To them I just want to say:
This is your brain,
And this is your brain on drugs: